Activity Summary:
During this educational podcast, Dr. Martin Maron highlights the latest advances in HCM presented at the ESC Congress 2025 in Madrid, Spain, August 29-September 1, 2025.

Noteworthy presentations, posters, and abstracts are presented from the conference that are of high clinical significance to improve HCM.

Activity Summary:
Hypertrophic Cardiomyopathy (HCM) remains a complex and frequently underdiagnosed cardiovascular condition that poses substantial challenges in recognition, risk stratification, and therapeutic management. During this Clinical Clip Video, Dr. Martin Maron highlights the latest advances in HCM presented at the ESC Congress 2025 in Madrid, Spain, August 29-September 1, 2025

Activity Summary:
To reinforce key learnings and support practical implementation of the HCM clips highlighting data presented at the 2025 ESC Congress, this library provides supplemental resources available for download or online reference. These materials are designed to provide clinicians with quick-reference tools, visual summaries, and ready-to-use content that can be revisited after the highlights video and/or podcast and can also be shared within clinical teams.

Summary of Downloadable Resources for this Activity Include:

• Clinical Snippet Highlights
  • One-page summaries of key ESC 2025 data designed to provide actionable takeaways in a quick-reference format for everyday clinical use.
• Downloadable Slides
  • A PDF version of the presentation slides, including data visuals, algorithms, and speaker insights. This is provide to provide learners a structured overview of each topic which is ideal for review, team meetings or local education.
• Podcast Transcript
  • A PDF version of the transcripts of the podcast for learners who prefer to read along or save for future reference.

This activity is not designated for continuing education credit. This is in no way a reflection of the integrity or quality of the content.

Activity Summary:
Stay informed on the go with our expert-led podcast series dedicated to stroke prevention. Across seven short episodes, Dr.'s C. Michael Gibson and Manesh Patel explore the shifting landscape of antithrombotic therapy—especially the potential role of Factor XIa inhibitors. From trial data to clinical applications, this series distills what you need to know to enhance patient care and reduce stroke risk.

Activity Summary:
The introduction of kinase inhibitors has significantly impacted the treatment landscape of plexiform neurofibromas (PN) associated with neurofibromatosis type 1 (NF1). In this Clinical Clip activity from the 2025 Annual Oncology Meeting, noteworthy data in NF1-PN has been summarized and evaluated by Dr. Amy Armstrong. This activity is AMA/ABS/ANCC/ACPE accredited for one-year.

Activity Summary:
This interactive webcast will feature dynamic case studies that encourage participants to apply clinical reasoning and make evidence-based decisions in real time in a fun and engaging manner. Attendees will have the unique opportunity to engage with leading experts in COPD, who will share their insights and experiences, facilitating a richer understanding of current treatment paradigms and research advancements.

Activity Summary:
Immune thrombocytopenic purpura (ITP) is an acquired autoimmune disorder marked by reduced platelet counts, purpura, and bleeding episodes driven by antiplatelet autoantibodies. Diagnosis remains one of exclusion, requiring careful differentiation from other causes of thrombocytopenia. Advances in pediatric ITP treatment are ushering in an era of precision medicine, integrating novel immunomodulatory therapies and personalized treatment approaches to optimize patient care. Recent research has introduced targeted pharmacological agents that address immune dysregulation, refining treatment protocols to align with individual patient profiles. The evolving landscape of pediatric ITP care calls for a comprehensive, evidence-driven approach, combining established therapies with innovative strategies to enhance efficacy and long-term disease management.

In this lecture library, Dr. Cindy Neunert, provides expert insights into emerging data on ITP pathophysiology, diagnosis, and treatment, equipping healthcare providers with the knowledge to translate new research into clinical practice and improve pediatric patient care.

Activity Summary:
Stroke prevention continues to challenge clinicians, especially when balancing effective anticoagulation with the risks of bleeding. During this video series, Dr.'s C. Michael Gibson and Manesh Patel provide rapid updates on the latest science shaping stroke prevention. Each 10–15-minute episode delivers digestible insights on topics such as emerging anticoagulation strategies, residual stroke risk, and clinical trial takeaways. This series is perfect for time-pressed healthcare professionals as it offers actionable knowledge designed to support evidence-based decision-making.

Activity Summary:
Myasthenia Gravis (MG) has had significant advances, however critical gaps persist in optimizing care. Challenges include variability in diagnostic accuracy, particularly in seronegative cases, and a limited adoption of newer, more sensitive testing modalities. Additionally, the evolving treatment landscape—with emerging therapies such as complement inhibitors and FcRn antagonists—highlights the need for clinicians to stay informed about the latest evidence and integrate these options into personalized care strategies. Addressing these gaps is crucial to improving patient care, enhancing quality of life, and reducing the burden of long-term side effects associated with traditional treatments.

This special edition podcast series with Dr. Nicholas Silvestri enables healthcare providers to engage with evidence-based insights and practical guidance on MG management at their convenience. The podcast format is ideal for professionals to access while commuting, during breaks, or between patient appointments, providing targeted learning without disrupting their workflow.

Activity Summary:
Pulmonary hypertension among patients with interstitial lung diseases (ILD-PH) is associated with increased morbidity, mortality, and healthcare burden and is currently under-recognized in clinical practice. To improve outcomes, early detection, timely diagnosis, and treatment of this complication among patients with ILD is an urgent priority.

Throughout this case-based presentation, Dr. Jean Elwing informs and guides on the latest insights to screen for, detect, accurately diagnose, and assess the severity of ILD-PH. Dr. Elwing also includes a discussion on identifying the right time and patient for a right heart catheterization, as it represents a complex and confounding decision in current clinical practice.